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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cacbefc00da194828d2f1a3e656f14c71b7481ca5bc27f3b7224bca1bb2dbd9' 
  AND token = 'ksp0nJwMKiUvsBVQsOznTh0hKamw4fTP7NG6yV0WsrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}