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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eba891f6e80f61a27a777f502b5efa94236ccda35bf7bdc2c8b64b0e75aa0757' 
  AND token = 'mO5b8adh4PvPEOUWmQQjTp+f+/W8Rdp0B5oktuFlD38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}