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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a847f26bff78cc05e2d065e8e975d480ccc9ea61e6ea250038f222985bce189b' 
  AND token = 'Oro16OHcBSMU8pn/8kPLkJPwqbLzd1Rskqjc9eHrJDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}