SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a4ca19173ac5897a83207f89636f40ad067dc9f702c903fcc5b2526f8921a51' 
  AND token = 'uZj7kfIszDSCCe/ape+p64bSpSpl/loDrS6wqEWakFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}