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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '625a7ea1fc50c5f8b549bb8450ee8977f1b0e252da60006a51f43b32181aacbe' 
  AND token = 'pDwh1nxZxo4uZ2HU+e3EdqQlrpSQyHOIH1Hx5peSZMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}