SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4b81ef23472ff2d7819aab9a12139f28c8bccf3c1b058a144ebc12bc12ac276' 
  AND token = 'yQFvsU9N0F7Ew7QLptgNJPG7lC9v4y626f7UxVDJdkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}