SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b0884a154154041ebeaebd5b0f54b34f04c66a31880fa7481442cfc8f8610e0' 
  AND token = '48Irnlp2Kjy2ALBXayytfMv5juzXYAtUm7u65/Xxcg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}