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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51ef2110a60c2867768d2be83e6f65a6c628849dea7f46f371cac4b68330188f' 
  AND token = 'WZtt/ulzyZ0bwnwqM9gsfw8OUvZ3Z+afvfUlxS4sgS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}