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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed083d7e9c88a2c5ee7d8e6c15ec74135af5a74fce329348805830081d1af421' 
  AND token = 'R0DGNMbF421Ufa1ifGjFMviO02GT2Qnhn6f9uN2rl5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}