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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c3d6c902398f7929c66202fcb6d777a47e154d1ebdf55e818ecc8c056a4228' 
  AND token = 'XcknYsOOVZ8bUQMk+V6bK7973/rDJ33M8ENtlQxp8hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}