SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf910e0da5da372b9d888e33cdfdcee3d9f4bbee9d0fab91691fd4cf607e4632' 
  AND token = 'tG4q36pevDTJOxBOjMtBZRr5hTdBBpeoudBpLNkke94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}