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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '612385c5975b1bd8f402c3f73c8b3a3dc782b5560cf52ec0d6e2cef4c643f1c6' 
  AND token = 'ZQ/zQZilXmgl7aboaKftZoMzq0VNoDXMRwkNk8GCAsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}