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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77cfb3bb8929c96a5165a5083f6445e93147dcdf6c0e1bdca364d1dc54c5468d' 
  AND token = 'N9pVIJ1leEjYLcByHNrdSHPHIIlF7u+1EZ6A0cXsomk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}