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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80a0b3fd332442accaf0078710bc585e87d2c5a0b1fc6c52c97821d77ce07d8' 
  AND token = 'Kf+lSzKB657/eyCIVP2mSpuvwKJ6f++B/D7UP5CxUiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}