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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c63dbdece73a3f810a55838b105504b3b7224ef08fbd905863dd700581fe5ebf' 
  AND token = 'lUpSCPm57EVCAxMNVpO3o8979hPXI5S5rqtwCSEaUj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}