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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d7338d92d2fe4188f0d14d74bbaf64044134db21b15c09e283189e6aaad2440' 
  AND token = 'vaxMY7qRiBIpQ2YRy0UPkFzsSwE/23rOYOQo67sOtx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}