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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '199daeba8472bcd6b1eba2d35e6616c6851cb0af35d2a74aa3067083001aa43f' 
  AND token = 'qvpIn+SNcgx3Ntz4fIEb0eHxME//xcUQV1noXHY4IzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}