SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6d0d01488cdb15007f2900bf03f2050c4f44e26155604ef1bda8724c6379231' 
  AND token = 'J0o1ZGS9SqaJSWS4X01MSTSQhTCUw2ptWYcKfMHa0us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}