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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e534d14b7eb804d1da3058072dc80f56b71ae8edcf855a053d02be715346cc89' 
  AND token = 'C5djmbWzGfp5oOY3ZWpCAjfar3oHujhiB07Ug/w0Aek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}