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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6e253af10f429a213af29b8e1eab7442173167d91ad18348ad5009f5ecf2c05' 
  AND token = '+67ckUZC5MxMnStchN9Gi+61pN5mb/kQM+qBibaWpT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}