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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ab44ae98a0095fef3e54dd605fd9289aab0131a43003173e450eb88b3837d3d' 
  AND token = 'u/py09E43HXrDrZrjxZxCIW/2oKhU664pXYtPxlauvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}