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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ad5db3a06c001a126e70a0577d8feed91a5e57fd652177295b924c76b17a95' 
  AND token = 'YQWATe96p0MP8WBGHOl11zE8FSyUcrhR5srElRPpXhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}