SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe800019938ac3d9dda4512d802eb66c643f7e1cfd93b72480087f71ccb2a7b1' 
  AND token = '1dmNj4e5tsuXw2bF9jKIbENmPjnk1deB83YGRRSxbzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}