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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42c61e6f9dbf8db9c8895a63a3eaa31b5e873ffb38a360119d33f134e5c0454' 
  AND token = 'uJEA1HvZqJBbm71cRIxh+Li6EPHEDyncBCsoi5stX9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}