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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ad21d2a07aafba54e664d68a39e1d7a3d9eb2f630f98cc8846afb942807e97' 
  AND token = 'AppgWf+gM99Tacrvoy7R2bqUVrKHAPtvBHPpLqf52zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}