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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f80d831746c54c3f3b751f28775c370af74cfa8f828a5e777919bb2cf6c531d' 
  AND token = 'E7oLIpuiC7UdVQb4AhOxSTRn7KBceTVGMfuM8LAZLBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}