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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50cc8f612e0ee190396be19de2418ee746ce09ea4f3545ab5b8d065c042012a7' 
  AND token = 'WGWRGoookWCXaBWGtWtDkTDXtylUyRIWuBLVTSJJqms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}