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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543afde542b9b63def8d5a55e08ce802075c6836798d41aab7387c77905b744e' 
  AND token = 'uMmtY799PbyaV3v+B17xqRQTUw2skOcKtkDjKHR/f2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}