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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c384597b22bba210a9cdee6049a8fc296a6aed993bd2f80ed7ab7a109cb8ce' 
  AND token = 'aAUeRA8PDltz1U3EIyzcpSYe1+MDXESiHHdYzDPgQwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}