SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a11b1d932cfad5676eca376e9dc08842eef74cdd0817ad65096a426c625f2268' 
  AND token = '5rRBJbuUVOYsymWH0ktoKgsQ7K5nA7tVMwyjDvb4TNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}