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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f3e0fae7e844035d524046b62fb0ac5a3abc98a264cc85e0d796099b24c259' 
  AND token = 'c7M2T6W6EB5rbyUKKPfxfGlGCpyv2ldQErIRXGSKVBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}