SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8d548267a9ce0bacb9c33d0556fde08d4c03e4dc6606cedcdad47898a0ba06' 
  AND token = 'mgqhYomKG6RrZdRsDIALLBAA4soI+P4sSMEMN3MZs58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}