SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bc1dcca1715ab8eed54d67669a0ca0bb3244ebabc7cb46ead2ccb3942644da7' 
  AND token = 'eeiJcVkMPbnVZ96aC6nFTV6LEN7JEOr6s4SxCKtKzUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}