SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22665423ffd3d17c09a17b159853fa778f0282d16fe6cfa495062503f1e1ff46' 
  AND token = 'P3KzQotRHYhSzJr1oKhZyfBAVDMDgz90IZPqkFI6jrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}