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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e999f90170ddc3bf423d0eba5c483ca5b5e14f4ec88b4481103f0d164eb25b0' 
  AND token = 'b1PaZbCKhcgaWsFFrlM2nhc2ul88RfvdYbbIhjz0iak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}