SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c84bacec6cc4b3a3a71d35f39f68a77b88c1550b5a5a108523e86df9c29aae87' 
  AND token = 'DlppQmF++dRPQ8dgx1QQ4Q61VaQrjLw46ZNPKHC4mvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}