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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb528772f3595d19bff78330284f7aaebec5a03a3de1f589975a6aed59514f8a' 
  AND token = 'PVUmnOfxpDk7tkyBesZTVpsqKdT6D9XqwpOH6SyVaAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}