SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc4453f51bb6f14889a9edc4b2e461577a2f74f640b04fa3ff9a2294fcb3a699' 
  AND token = 'fX0XhKW8dhZnOyy1Zt3DLIsUQ7pGS+do32k13WuR8Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}