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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a09f427ed2484ec85c21efca623d3d1ebba4dbaf5a72257f091641126ea8a58' 
  AND token = 'JafKPes8Hn0XYNjUr3CwFMse2IwxFfsYuIb+bzOuew0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}