SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8725a03ee44bfed1b18b112c76c6632967e8cbf2ba83a9fe61a57253d82d9454' 
  AND token = 'StNCPi6513UfeXYwvuQ+dcIFrcOGhhXnJx1fcH6piIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}