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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f48f1e2aae375f9f0a78124c228e97ae0d704d6e763f3c9d70667f4a6b210225' 
  AND token = 'GYSNztKt2oaGWipaGMHHhJTACgvl+FRfdRFyHaw+3wA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}