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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f8fedc8c4cbbcdd18f7559dc84004e96c4c2880f36c1e7e1eb2f40d5f427c4' 
  AND token = 't4lzW9NFB0C/uEEoaSrKwwyQqZrXo3VTv8/G0ZXD40w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}