SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730ccd08037a1428c69751380b173ab5ba0d2f1b52b574239949fb7432e7f3ae' 
  AND token = 'qFi3PAUzi40hCOVz991qtzl4vBQOKiRxIezGUuDPnEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}