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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f2a8b6036a358e36d558e53c8d190f2696edbf675332a53e9310d105107eea7' 
  AND token = 'ZVbHMp5YMjUe/NBGq6kcMSbL2Ji+gXK6uFPyayAKgh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}