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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '514111ed98f53b22320b21c09edee8c353bf4b0776e74adb4b55525377a7abcf' 
  AND token = 'zsDS7pdyL0k6ty/DaIpA5dKPv8qvaGkfggwCpZ0KCyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}