SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d74a17d2de7cb881f01dead64bf4b9fe9162103c38475573a35c9a72f6d0910' 
  AND token = 'PmWhhEzJ62hRNh36sHSDXStLDw2+fBdRZOV10Zwo/14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}