SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a50f9dba16560a14a463a0bb93b77b8701aac85fcec2d809ab9564cadd8155' 
  AND token = '8vNEEbetzbnkJaTNANQQ4Y8jVLyCBRS1rowWuh3/h0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}