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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '890d0a4b6394a30504ffb5fbf466bfae8651e289c0fe5f0c950e7bfee10b232d' 
  AND token = 'xOMisduu/JppJll4POLznU5zu49Gg0VnKVJWC5YUVLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}