SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e50f544c6a97a4383806abe8c63789e9b5c175be107033be3e52818d359b16e' 
  AND token = 'uXLIXnB43Cz1cRacczGx0EibScZOUOoxUrOkI/tANf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}