SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ccf9e25e1d509a742ea199e7139712ec44417d5a3a7da72a29bb80f8593a0e' 
  AND token = '2zm63DEAE/nlItMdpy257dv8lPmhnRgS8sZlQoSXNg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}